Genome-wide copy number variations in Bhutia equine breed using SNP genotyping data

Copy number variants (CNVs) have dynamic potential and evolutionary significance like other genetic variants, namely, single nucleotide polymorphisms, InDels, short tandem repeat inversion etc. Discovering CNVs leads to further speculation that the genomic DNA contains more changes than previously thought contributes phenotypic variation. are big fragments (> 1 kb) being duplicated or deleted. A bridge between variations supports be utilized in GWAS, which currently mostly based on SNPs. CNV, refers structural differences, influence gene expression can an indicator of numerous traits for improvement. There is a severe dearth research animals, especially equine. The present study investigates genomes Bhutia Equine breed genome-wide discovery using theAxiom™ Genotyping Array chip better understanding its had been unexplored till date. total 619 from 20 equines were identified with median average size as 49.394 kb 114.955 kb, respectively. Total 225 frequent CNVRs > 1% CNV frequency among them along singleton type. These contained 361 genes all. information obtained variation could identify economically advantageous features equine breed.